DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity [GO_0072586]

Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.

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Class
GO

DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity

ID: GO_0072586

Class

Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.

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Classification

enzyme regulator activity

Relationships

regulates: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

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], "short_form": "GO_0003918", "label": "DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity" } } ], "xrefs": [], "anatomy_channel_image": [], "pub_syn": [], "def_pubs": [ { "core": { "symbol": "", "iri": "http://flybase.org/reports/Unattributed", "types": [ "Entity", "Individual", "pub" ], "short_form": "Unattributed", "label": "" }, "FlyBase": "", "PubMed": "", "DOI": "" } ] }

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